Immunotherapy via PD-L1–presenting biomaterials leads to long-term islet graft survival

Antibody-mediated immune checkpoint blockade is a transformative immunotherapy for cancer. These same mechanisms can be repurposed for the control of destructive alloreactive immune responses in the transplantation setting. Here, we implement a synthetic biomaterial platform for the local delivery o...

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Detalles Bibliográficos
Autores principales: Coronel, María M., Martin, Karen E., Hunckler, Michael D., Barber, Graham, O’Neill, Eric B., Medina, Juan D., Opri, Enrico, McClain, Claire A., Batra, Lalit, Weaver, Jessica D., Lim, Hong S., Qiu, Peng, Botchwey, Edward A., Yolcu, Esma S., Shirwan, Haval, García, Andrés J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455180/
https://www.ncbi.nlm.nih.gov/pubmed/32923626
http://dx.doi.org/10.1126/sciadv.aba5573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455180/
https://www.ncbi.nlm.nih.gov/pubmed/32923626
http://dx.doi.org/10.1126/sciadv.aba5573

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