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Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel

Connexin family proteins assemble into hexameric channels called hemichannels/connexons, which function as transmembrane channels or dock together to form gap junction intercellular channels (GJIChs). We determined the cryo–electron microscopy structures of human connexin 31.3 (Cx31.3)/GJC3 hemichan...

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Detalles Bibliográficos
Autores principales: Lee, Hyuk-Joon, Jeong, Hyeongseop, Hyun, Jaekyung, Ryu, Bumhan, Park, Kunwoong, Lim, Hyun-Ho, Yoo, Jejoong, Woo, Jae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455182/
https://www.ncbi.nlm.nih.gov/pubmed/32923625
http://dx.doi.org/10.1126/sciadv.aba4996