Disruption in ACTL7A causes acrosomal ultrastructural defects in human and mouse sperm as a novel male factor inducing early embryonic arrest

Early embryonic arrest is a challenge for in vitro fertilization (IVF). No genetic factors were previously revealed in the sperm-derived arrest of embryonic development. Here, we reported two infertile brothers presenting normal in conventional semen analysis, but both couples had no embryos for tra...

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Detalles Bibliográficos
Autores principales: Xin, Aijie, Qu, Ronggui, Chen, Guowu, Zhang, Ling, Chen, Junling, Tao, Chengqiu, Fu, Jing, Tang, Jianan, Ru, Yanfei, Chen, Ying, Peng, Xiandong, Shi, Huijuan, Zhang, Feng, Sun, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455188/
https://www.ncbi.nlm.nih.gov/pubmed/32923619
http://dx.doi.org/10.1126/sciadv.aaz4796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455188/
https://www.ncbi.nlm.nih.gov/pubmed/32923619
http://dx.doi.org/10.1126/sciadv.aaz4796

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