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Unmasking selective path integration deficits in Alzheimer’s disease risk carriers

Alzheimer’s disease (AD) manifests with progressive memory loss and spatial disorientation. Neuropathological studies suggest early AD pathology in the entorhinal cortex (EC) of young adults at genetic risk for AD (APOE ε4-carriers). Because the EC harbors grid cells, a likely neural substrate of pa...

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Detalles Bibliográficos
Autores principales: Bierbrauer, Anne, Kunz, Lukas, Gomes, Carlos A., Luhmann, Maike, Deuker, Lorena, Getzmann, Stephan, Wascher, Edmund, Gajewski, Patrick D., Hengstler, Jan G., Fernandez-Alvarez, Marina, Atienza, Mercedes, Cammisuli, Davide M., Bonatti, Francesco, Pruneti, Carlo, Percesepe, Antonio, Bellaali, Youssef, Hanseeuw, Bernard, Strange, Bryan A., Cantero, Jose L., Axmacher, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455192/
https://www.ncbi.nlm.nih.gov/pubmed/32923622
http://dx.doi.org/10.1126/sciadv.aba1394