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Unmasking selective path integration deficits in Alzheimer’s disease risk carriers
Alzheimer’s disease (AD) manifests with progressive memory loss and spatial disorientation. Neuropathological studies suggest early AD pathology in the entorhinal cortex (EC) of young adults at genetic risk for AD (APOE ε4-carriers). Because the EC harbors grid cells, a likely neural substrate of pa...
Autores principales: | Bierbrauer, Anne, Kunz, Lukas, Gomes, Carlos A., Luhmann, Maike, Deuker, Lorena, Getzmann, Stephan, Wascher, Edmund, Gajewski, Patrick D., Hengstler, Jan G., Fernandez-Alvarez, Marina, Atienza, Mercedes, Cammisuli, Davide M., Bonatti, Francesco, Pruneti, Carlo, Percesepe, Antonio, Bellaali, Youssef, Hanseeuw, Bernard, Strange, Bryan A., Cantero, Jose L., Axmacher, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455192/ https://www.ncbi.nlm.nih.gov/pubmed/32923622 http://dx.doi.org/10.1126/sciadv.aba1394 |
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