Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction

Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous implications of mitochondrial dysfunction for neuronal metabolism in vivo are poorly understood. Here, we profiled the cell-specific proteome of Purkinj...

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Detalles Bibliográficos
Autores principales: Motori, E., Atanassov, I., Kochan, S. M. V., Folz-Donahue, K., Sakthivelu, V., Giavalisco, P., Toni, N., Puyal, J., Larsson, N.-G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455195/
https://www.ncbi.nlm.nih.gov/pubmed/32923630
http://dx.doi.org/10.1126/sciadv.aba8271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455195/
https://www.ncbi.nlm.nih.gov/pubmed/32923630
http://dx.doi.org/10.1126/sciadv.aba8271

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