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Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability

Hepatitis B virus (HBV) is an important but difficult to study human pathogen. Most basics of the hepadnaviral life-cycle were unraveled using duck HBV (DHBV) as a model although DHBV has a capsid protein (CP) comprising ~260 rather than ~180 amino acids. Here we present high-resolution structures o...

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Detalles Bibliográficos
Autores principales: Makbul, Cihan, Nassal, Michael, Böttcher, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455244/
https://www.ncbi.nlm.nih.gov/pubmed/32795390
http://dx.doi.org/10.7554/eLife.57277