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Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations

Inefficient injection of microparticles through conventional hypodermic needles can impose serious challenges on clinical translation of biopharmaceutical drugs and microparticle-based drug formulations. This study aims to determine the important factors affecting microparticle injectability and est...

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Detalles Bibliográficos
Autores principales: Sarmadi, Morteza, Behrens, Adam M., McHugh, Kevin J., Contreras, Hannah T. M., Tochka, Zachary L., Lu, Xueguang, Langer, Robert, Jaklenec, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455482/
https://www.ncbi.nlm.nih.gov/pubmed/32923598
http://dx.doi.org/10.1126/sciadv.abb6594