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Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations
Inefficient injection of microparticles through conventional hypodermic needles can impose serious challenges on clinical translation of biopharmaceutical drugs and microparticle-based drug formulations. This study aims to determine the important factors affecting microparticle injectability and est...
Autores principales: | Sarmadi, Morteza, Behrens, Adam M., McHugh, Kevin J., Contreras, Hannah T. M., Tochka, Zachary L., Lu, Xueguang, Langer, Robert, Jaklenec, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455482/ https://www.ncbi.nlm.nih.gov/pubmed/32923598 http://dx.doi.org/10.1126/sciadv.abb6594 |
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