Cargando…
Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors
It is widely understood that CRISPR-Cas9 technology is revolutionary, with well-recognized issues including the potential for off-target edits and the attendant need for spatiotemporal control of editing. Here, we describe a far-red light (FRL)–activated split-Cas9 (FAST) system that can robustly in...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455487/ https://www.ncbi.nlm.nih.gov/pubmed/32923591 http://dx.doi.org/10.1126/sciadv.abb1777 |