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Engineering bacterial outer membrane vesicles as transdermal nanoplatforms for photo-TRAIL–programmed therapy against melanoma

Melanoma is an aggressive cancer with rapid progression, relapse, and metastasis. Systemic therapies for melanoma exhibit limited anticancer potential and high toxicity. Here, we developed the outer membrane vesicles derived from transgenic Escherichia coli, modified with α(v)β(3) integrin peptide t...

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Detalles Bibliográficos
Autores principales: Peng, Li-Hua, Wang, Mao-Ze, Chu, Yang, Zhang, Lei, Niu, Jie, Shao, Hai-Tao, Yuan, Tie-Jun, Jiang, Zhi-Hong, Gao, Jian-Qing, Ning, Xing-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455490/
https://www.ncbi.nlm.nih.gov/pubmed/32923586
http://dx.doi.org/10.1126/sciadv.aba2735