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Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy

Activation of the innate immune system and natural killer (NK) cells has been a key effort in cancer immunotherapy research. Here, we report a nanoparticle-based trispecific NK cell engager (nano-TriNKE) platform that can target epidermal growth factor receptor (EGFR)–overexpressing tumors and promo...

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Detalles Bibliográficos
Autores principales: Au, Kin Man, Park, Steven I., Wang, Andrew Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455497/
https://www.ncbi.nlm.nih.gov/pubmed/32923587
http://dx.doi.org/10.1126/sciadv.aba8564