Scaffold morphing of arbidol (umifenovir) in search of multi-targeting therapy halting the interaction of SARS-CoV-2 with ACE2 and other proteases involved in COVID-19

The rapid emergence of novel coronavirus, SARS-coronavirus 2 (SARS-CoV-2), originated from Wuhan, China, imposed a global health emergency. Angiotensin-converting enzyme 2 (ACE2) receptor serves as an entry point for this deadly virus while the proteases like furin, transmembrane protease serine 2 (...

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Detalles Bibliográficos
Autores principales: Choudhary, Shalki, Silakari, Om
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455547/
https://www.ncbi.nlm.nih.gov/pubmed/32866534
http://dx.doi.org/10.1016/j.virusres.2020.198146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455547/
https://www.ncbi.nlm.nih.gov/pubmed/32866534
http://dx.doi.org/10.1016/j.virusres.2020.198146

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