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Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å

Gap junctions establish direct pathways for cells to transfer metabolic and electrical messages. The local lipid environment is known to affect the structure, stability and intercellular channel activity of gap junctions; however, the molecular basis for these effects remains unknown. Here, we incor...

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Detalles Bibliográficos
Autores principales: Flores, Jonathan A., Haddad, Bassam G., Dolan, Kimberly A., Myers, Janette B., Yoshioka, Craig C., Copperman, Jeremy, Zuckerman, Daniel M., Reichow, Steve L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455559/
https://www.ncbi.nlm.nih.gov/pubmed/32859914
http://dx.doi.org/10.1038/s41467-020-18120-5