Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis

Calcific aortic valve stenosis (CAVS) is a frequent heart disease with significant morbidity and mortality. Recent genomic studies have identified a locus near the gene PALMD (palmdelphin) strongly associated with CAVS. Here, we show that genetically-determined expression of PALMD in the aortic valv...

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Detalles Bibliográficos
Autores principales: Li, Zhonglin, Gaudreault, Nathalie, Arsenault, Benoit J., Mathieu, Patrick, Bossé, Yohan, Thériault, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455695/
https://www.ncbi.nlm.nih.gov/pubmed/32859967
http://dx.doi.org/10.1038/s42003-020-01210-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455695/
https://www.ncbi.nlm.nih.gov/pubmed/32859967
http://dx.doi.org/10.1038/s42003-020-01210-x

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