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Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis
Calcific aortic valve stenosis (CAVS) is a frequent heart disease with significant morbidity and mortality. Recent genomic studies have identified a locus near the gene PALMD (palmdelphin) strongly associated with CAVS. Here, we show that genetically-determined expression of PALMD in the aortic valv...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455695/ https://www.ncbi.nlm.nih.gov/pubmed/32859967 http://dx.doi.org/10.1038/s42003-020-01210-x |