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Rapid high-yield expression and purification of fully post-translationally modified recombinant clusterin and mutants
The first described and best known mammalian secreted chaperone, abundant in human blood, is clusterin. Recent independent studies are now exploring the potential use of clusterin as a therapeutic in a variety of disease contexts. In the past, the extensive post-translational processing of clusterin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455699/ https://www.ncbi.nlm.nih.gov/pubmed/32859921 http://dx.doi.org/10.1038/s41598-020-70990-3 |