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Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology

The general anesthetic ketamine has been repurposed by physicians as an anti-depressant and by the public as a recreational drug. However, ketamine use can cause extensive pathological changes, including ketamine cystitis. The mechanisms of ketamine’s anti-depressant and adverse effects remain poorl...

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Detalles Bibliográficos
Autores principales: Chen, Huan, Vandorpe, David H., Xie, Xiang, Alper, Seth L., Zeidel, Mark L., Yu, Weiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455701/
https://www.ncbi.nlm.nih.gov/pubmed/32859919
http://dx.doi.org/10.1038/s41467-020-18167-4