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A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data

A common analysis of single-cell sequencing data includes clustering of cells and identifying differentially expressed genes (DEGs). How cell clusters are defined has important consequences for downstream analyses and the interpretation of results, but is often not straightforward. To address this d...

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Detalles Bibliográficos
Autores principales: Vandenbon, Alexis, Diez, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455704/
https://www.ncbi.nlm.nih.gov/pubmed/32859930
http://dx.doi.org/10.1038/s41467-020-17900-3