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Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo

Solid organ transplantation is a lifesaving therapy for patients with end-organ disease. Current immunosuppression protocols are not designed to target antigen-specific alloimmunity and are uncapable of preventing chronic allograft injury. As myeloid-derived suppressor cells (MDSCs) are potent immun...

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Detalles Bibliográficos
Autores principales: Cai, Songjie, Choi, John Y., Borges, Thiago J., Zhang, Hengcheng, Miao, Ji, Ichimura, Takaharu, Li, Xiaofei, Xu, Simiao, Chu, Philip, Eskandari, Siawosh K., Allos, Hazim, Alhaddad, Juliano B., Muhsin, Saif A., Yatim, Karim, Riella, Leonardo V., Sage, Peter T., Chandraker, Anil K., Azzi, Jamil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455707/
https://www.ncbi.nlm.nih.gov/pubmed/32859934
http://dx.doi.org/10.1038/s41598-020-71289-z