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Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo
Solid organ transplantation is a lifesaving therapy for patients with end-organ disease. Current immunosuppression protocols are not designed to target antigen-specific alloimmunity and are uncapable of preventing chronic allograft injury. As myeloid-derived suppressor cells (MDSCs) are potent immun...
Autores principales: | Cai, Songjie, Choi, John Y., Borges, Thiago J., Zhang, Hengcheng, Miao, Ji, Ichimura, Takaharu, Li, Xiaofei, Xu, Simiao, Chu, Philip, Eskandari, Siawosh K., Allos, Hazim, Alhaddad, Juliano B., Muhsin, Saif A., Yatim, Karim, Riella, Leonardo V., Sage, Peter T., Chandraker, Anil K., Azzi, Jamil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455707/ https://www.ncbi.nlm.nih.gov/pubmed/32859934 http://dx.doi.org/10.1038/s41598-020-71289-z |
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