Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function

Cholesterol 25-hydroxylase (CH25H) encodes the enzyme that converts cholesterol to 25-hydroxycholesterol (25-HC). 25-HC has been demonstrated to be involved in the pathogenesis of inflammatory bowel disease. However, the role of CH25H in experimental colitis remains unknown. Dextran sulfate sodium (...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheng, Na, Ma, Zhongnan, Zhou, Yi, Xu, Juan, Gao, Yan, Fu, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455728/
https://www.ncbi.nlm.nih.gov/pubmed/32859970
http://dx.doi.org/10.1038/s41598-020-71198-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455728/
https://www.ncbi.nlm.nih.gov/pubmed/32859970
http://dx.doi.org/10.1038/s41598-020-71198-1

Ejemplares similares