Cargando…

Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function

Cholesterol 25-hydroxylase (CH25H) encodes the enzyme that converts cholesterol to 25-hydroxycholesterol (25-HC). 25-HC has been demonstrated to be involved in the pathogenesis of inflammatory bowel disease. However, the role of CH25H in experimental colitis remains unknown. Dextran sulfate sodium (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheng, Na, Ma, Zhongnan, Zhou, Yi, Xu, Juan, Gao, Yan, Fu, Xin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455728/ https://www.ncbi.nlm.nih.gov/pubmed/32859970 http://dx.doi.org/10.1038/s41598-020-71198-1

Ejemplares similares

Genomics and proteomics of vertebrate cholesterol ester lipase (LIPA) and cholesterol 25-hydroxylase (CH25H)
por: Holmes, Roger S., et al.
Publicado: (2011)

Research progress on the mechanism of cholesterol-25-hydroxylase in intestinal immunity
por: Zhong, Guoqiang, et al.
Publicado: (2023)

Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis
por: Liberti, Assunta, et al.
Publicado: (2017)

Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis
por: Dong, Zeyu, et al.
Publicado: (2022)

Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis
por: Keely, Simon, et al.
Publicado: (2013)

Cholesterol 25-hydroxylase negatively regulates porcine intestinal coronavirus replication by the production of 25-hydroxycholesterol
por: Zhang, Yunhang, et al.
Publicado: (2019)

Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol
por: Wang, Yuyang, et al.
Publicado: (2023)

Cholesterol 25‐Hydroxylase inhibits SARS‐CoV‐2 and other coronaviruses by depleting membrane cholesterol
por: Wang, Shaobo, et al.
Publicado: (2020)

Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice
por: Noebauer, Britta, et al.
Publicado: (2017)

Cholesterol 25-hydroxylase suppresses porcine deltacoronavirus infection by inhibiting viral entry
por: Ke, Wenting, et al.
Publicado: (2021)

Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol
por: Xie, Tingting, et al.
Publicado: (2019)

Cholesterol 25-hydroxylase (CH25H) as a promoter of adipose tissue inflammation in obesity and diabetes
por: Russo, Lucia, et al.
Publicado: (2020)

Dual-Role of Cholesterol‐25‐Hydroxylase in Regulating Hepatitis B Virus Infection and Replication
por: Wei, Qi, et al.
Publicado: (2022)

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
por: Zang, Ruochen, et al.
Publicado: (2020)

Role of Cholesterol 25-Hydroxylase (Ch25h) in Mediating Innate Immune Responses to Streptococcus pneumoniae Infection
por: Cho, Soo Jung, et al.
Publicado: (2023)

Dynamics of Prolyl Hydroxylases Levels During Disease Progression in Experimental Colitis
por: Bakshi, Hamid A., et al.
Publicado: (2019)

Cinobufacini ameliorates experimental colitis via modulating the composition of gut microbiota
por: Bai, Yongfeng, et al.
Publicado: (2019)

Obacunone Protects Against Ulcerative Colitis in Mice by Modulating Gut Microbiota, Attenuating TLR4/NF-κB Signaling Cascades, and Improving Disrupted Epithelial Barriers
por: Luo, Xiaoping, et al.
Publicado: (2020)

Bifidobacterium breve Alleviates DSS-Induced Colitis in Mice by Maintaining the Mucosal and Epithelial Barriers and Modulating Gut Microbes
por: Niu, Meng-Meng, et al.
Publicado: (2022)

Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury
por: Chen, Chen, et al.
Publicado: (2022)

Mannose ameliorates experimental colitis by protecting intestinal barrier integrity
por: Dong, Lijun, et al.
Publicado: (2022)

Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis
por: Lee, June-Chul, et al.
Publicado: (2017)

Modulation of Gut Barrier Functions in Ulcerative Colitis by Hyaluronic Acid System
por: Kotla, Niranjan G., et al.
Publicado: (2021)

Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms
por: Chen, Yongzhi, et al.
Publicado: (2014)

Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis
por: Naydenov, Nayden G., et al.
Publicado: (2016)

Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis
por: Olli, Kristine E, et al.
Publicado: (2020)

Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota
por: Hu, Lin, et al.
Publicado: (2019)

Fecal microbiota transplantation ameliorates experimental colitis via gut microbiota and T-cell modulation
por: Wen, Xin, et al.
Publicado: (2021)

Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function
por: Manresa, Mario C., et al.
Publicado: (2017)

Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells
por: Xu, Dongke, et al.
Publicado: (2022)

An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression
por: Kovács, Kinga Bernadett, et al.
Publicado: (2023)

Novel Potassium-Competitive Acid Blocker, Tegoprazan, Protects Against Colitis by Improving Gut Barrier Function
por: Son, Mijeong, et al.
Publicado: (2022)

Modulation of Gut Microbiome Composition and Function in Experimental Colitis Treated with Sulfasalazine
por: Zheng, Haihui, et al.
Publicado: (2017)

Regulatory Effect of Lactobacillus brevis Bmb6 on Gut Barrier Functions in Experimental Colitis
por: Shin, Mi-Young, et al.
Publicado: (2020)

Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse
por: Meljon, Anna, et al.
Publicado: (2014)

PD-1 deficiency protects experimental colitis via alteration of gut microbiota
por: Park, Seong Jeong, et al.
Publicado: (2017)

Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry
por: Zhang, Ya, et al.
Publicado: (2019)

Protective role of 1,25(OH)(2)vitamin D(3) in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice
por: Zhao, Hongwei, et al.
Publicado: (2012)

Carboxypeptidase E Modulates Intestinal Immune Homeostasis and Protects against Experimental Colitis in Mice
por: Bär, Florian, et al.
Publicado: (2014)

Gracilaria lemaneiformis polysaccharides alleviate colitis by modulating the gut microbiota and intestinal barrier in mice
por: Lu, Si-Yuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i5d6bk9mnu4beh6605e0q89gdc