Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-κB through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model

BACKGROUND: Mast cells play an important role in early immune reactions in the brain by degranulation and the consequent inflammatory response. Our aim of the study is to investigate the effects of rh-relaxin-2 on mast cells and the underlying mechanisms in a germinal matrix hemorrhage (GMH) rat mod...

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Detalles Bibliográficos
Autores principales: Li, Peng, Zhao, Gang, Chen, Fanfan, Ding, Yan, Wang, Tianyi, Liu, Shengpeng, Lu, Weitian, Xu, Weilin, Flores, Jerry, Ocak, Umut, Zhang, Tongyu, Zhang, John H., Tang, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455905/
https://www.ncbi.nlm.nih.gov/pubmed/32859236
http://dx.doi.org/10.1186/s12974-020-01926-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455905/
https://www.ncbi.nlm.nih.gov/pubmed/32859236
http://dx.doi.org/10.1186/s12974-020-01926-x

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