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Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer

BACKGROUND: Lysine succinylation is an emerging posttranslational modification that has garnered increased attention recently, but its role in gastric cancer (GC) remains underexplored. METHODS: Proteomic quantification of lysine succinylation was performed in human GC tissues and adjacent normal ti...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Zhang, Chen, Zhao, Ting, Su, Zhongping, Li, Mengjing, Hu, Jiancheng, Wen, Jianfei, Shen, Jiajia, Wang, Chao, Pan, Jinshun, Mu, Xianmin, Ling, Tao, Li, Yingchang, Wen, Hao, Zhang, Xiaoren, You, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455916/
https://www.ncbi.nlm.nih.gov/pubmed/32859246
http://dx.doi.org/10.1186/s13046-020-01681-0