mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington’s disease

Repressor element 1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is a transcription repressor and its expression is regulated by the Wnt pathway through β-catenin. Metabotropic glutamate receptor 5 (mGluR5) signaling plays a key role in controlling neuronal gene expr...

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Detalles Bibliográficos
Autores principales: de Souza, Jéssica M., Abd-Elrahman, Khaled S., Ribeiro, Fabiola M., Ferguson, Stephen S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456045/
https://www.ncbi.nlm.nih.gov/pubmed/32859226
http://dx.doi.org/10.1186/s13041-020-00657-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456045/
https://www.ncbi.nlm.nih.gov/pubmed/32859226
http://dx.doi.org/10.1186/s13041-020-00657-7

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