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mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington’s disease

Repressor element 1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is a transcription repressor and its expression is regulated by the Wnt pathway through β-catenin. Metabotropic glutamate receptor 5 (mGluR5) signaling plays a key role in controlling neuronal gene expr...

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Detalles Bibliográficos
Autores principales:	de Souza, Jéssica M., Abd-Elrahman, Khaled S., Ribeiro, Fabiola M., Ferguson, Stephen S. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456045/ https://www.ncbi.nlm.nih.gov/pubmed/32859226 http://dx.doi.org/10.1186/s13041-020-00657-7

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