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RNA abasic sites in yeast and human cells

RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that, in yeast and human cells, RNA abasic sites are prevalent. When a base is lost from RNA, the remaining ribose is found as a closed-ring or a...

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Detalles Bibliográficos
Autores principales: Liu, Yaojuan, Rodriguez, Yesenia, Ross, Robert L., Zhao, Ruoxia, Watts, Jason A., Grunseich, Christopher, Bruzel, Alan, Li, Dongjun, Burdick, Joshua T., Prasad, Rajendra, Crouch, Robert J., Limbach, Patrick A., Wilson, Samuel H., Cheung, Vivian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456069/
https://www.ncbi.nlm.nih.gov/pubmed/32788345
http://dx.doi.org/10.1073/pnas.2011511117