Cargando…
RNA abasic sites in yeast and human cells
RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that, in yeast and human cells, RNA abasic sites are prevalent. When a base is lost from RNA, the remaining ribose is found as a closed-ring or a...
Autores principales: | Liu, Yaojuan, Rodriguez, Yesenia, Ross, Robert L., Zhao, Ruoxia, Watts, Jason A., Grunseich, Christopher, Bruzel, Alan, Li, Dongjun, Burdick, Joshua T., Prasad, Rajendra, Crouch, Robert J., Limbach, Patrick A., Wilson, Samuel H., Cheung, Vivian G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456069/ https://www.ncbi.nlm.nih.gov/pubmed/32788345 http://dx.doi.org/10.1073/pnas.2011511117 |
Ejemplares similares
-
cis Elements that Mediate RNA Polymerase II Pausing Regulate Human Gene Expression
por: Watts, Jason A., et al.
Publicado: (2019) -
Evidence for Abasic Site Sugar Phosphate-Mediated Cytotoxicity in Alkylating Agent Treated Saccharomyces cerevisiae
por: Heacock, Michelle, et al.
Publicado: (2012) -
Nanopore-based direct sequencing of RNA transcripts with 10 different modified nucleotides reveals gaps in existing technology
por: Burdick, Joshua T, et al.
Publicado: (2023) -
Nucleosomal embedding reshapes the dynamics of abasic sites
por: Bignon, Emmanuelle, et al.
Publicado: (2020) -
The chemical stability of abasic RNA compared to abasic DNA
por: Küpfer, Pascal A., et al.
Publicado: (2007)