Cargando…

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

Mucosal-associated invariant T (MAIT) cells are innate T lymphocytes activated by bacteria that produce vitamin B2 metabolites. Mouse models of infection have demonstrated a role for MAIT cells in antimicrobial defense. However, proposed protective roles of MAIT cells in human infections remain unpr...

Descripción completa

Detalles Bibliográficos
Autores principales: Preciado-Llanes, Lorena, Aulicino, Anna, Canals, Rocío, Moynihan, Patrick J., Zhu, Xiaojun, Jambo, Ndaru, Nyirenda, Tonney S., Kadwala, Innocent, Sousa Gerós, Ana, Owen, Siân V., Jambo, Kondwani C., Kumwenda, Benjamin, Veerapen, Natacha, Besra, Gurdyal S., Gordon, Melita A., Hinton, Jay C. D., Napolitani, Giorgio, Salio, Mariolina, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456131/
https://www.ncbi.nlm.nih.gov/pubmed/32788367
http://dx.doi.org/10.1073/pnas.2007472117