Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

Virus entry is a multistep process. It initiates when the virus attaches to the host cell and ends when the viral contents reach the cytosol. Genetically unrelated viruses can subvert analogous subcellular mechanisms and use similar trafficking pathways for successful entry. Antiviral strategies tar...

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Detalles Bibliográficos
Autores principales: Kang, Yuan-Lin, Chou, Yi-ying, Rothlauf, Paul W., Liu, Zhuoming, Soh, Timothy K., Cureton, David, Case, James Brett, Chen, Rita E., Diamond, Michael S., Whelan, Sean P. J., Kirchhausen, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456157/
https://www.ncbi.nlm.nih.gov/pubmed/32764148
http://dx.doi.org/10.1073/pnas.2007837117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456157/
https://www.ncbi.nlm.nih.gov/pubmed/32764148
http://dx.doi.org/10.1073/pnas.2007837117

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