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Glucocorticoid Resistance in Premature Adrenarche and PCOS: From Childhood to Adulthood

CONTEXT: We hypothesize that impaired glucocorticoid sensitivity (GC sensitivity) plays a role in the development of premature adrenarche (PA) and polycystic ovarian syndrome (PCOS) by increasing androgen synthesis. OBJECTIVE: To study glucocorticoid sensitivity in vitro in subjects with PA and PCOS...

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Detalles Bibliográficos
Autores principales: Panayiotopoulos, Aristotle, Bhangoo, Amrit, Khurana, Divya, Ten, Svetlana, Michl, Josef, Ghanny, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456159/
https://www.ncbi.nlm.nih.gov/pubmed/32904537
http://dx.doi.org/10.1210/jendso/bvaa111