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PET/CT Imaging with an (18)F-Labeled Galactodendritic Unit in a Galectin-1–Overexpressing Orthotopic Bladder Cancer Model

Galectins are carbohydrate-binding proteins overexpressed in bladder cancer (BCa) cells. Dendritic galactose moieties have a high affinity for galectin-expressing tumor cells. We radiolabeled a dendritic galactose carbohydrate with (18)F ((18)F-labeled galactodendritic unit 4) and examined its poten...

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Detalles Bibliográficos
Autores principales: Pereira, Patricia M.R., Roberts, Sheryl, Figueira, Flávio, Tomé, João P.C., Reiner, Thomas, Lewis, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456169/
https://www.ncbi.nlm.nih.gov/pubmed/32005776
http://dx.doi.org/10.2967/jnumed.119.236430