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Ancestral and derived transcriptional enhancers share regulatory sequence and a pleiotropic site affecting chromatin accessibility

The diversity of forms in multicellular organisms originates largely from the spatial redeployment of developmental genes [S. B. Carroll, Cell 134, 25–36 (2008)]. Several scenarios can explain the emergence of cis-regulatory elements that govern novel aspects of a gene expression pattern [M. Rebeiz,...

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Detalles Bibliográficos
Autores principales: Xin, Yaqun, Le Poul, Yann, Ling, Liucong, Museridze, Mariam, Mühling, Bettina, Jaenichen, Rita, Osipova, Elena, Gompel, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456186/
https://www.ncbi.nlm.nih.gov/pubmed/32778581
http://dx.doi.org/10.1073/pnas.2004003117