3D model of harlequin ichthyosis reveals inflammatory therapeutic targets

The biology of harlequin ichthyosis (HI), a devastating skin disorder caused by loss-of-function mutations in the gene ABCA12, is poorly understood, and to date, no satisfactory treatment has been developed. We sought to investigate pathomechanisms of HI that could lead to the identification of new...

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Detalles Bibliográficos
Autores principales: Enjalbert, Florence, Dewan, Priya, Caley, Matthew P., Jones, Eleri M., Morse, Mary A., Kelsell, David P., Enright, Anton J., O’Toole, Edel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456239/
https://www.ncbi.nlm.nih.gov/pubmed/32544098
http://dx.doi.org/10.1172/JCI132987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456239/
https://www.ncbi.nlm.nih.gov/pubmed/32544098
http://dx.doi.org/10.1172/JCI132987

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