Transgenic inhibition of astroglial NF-κB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma

BACKGROUND: Glia-driven neuroinflammation promotes neuron injury in glaucoma that is a chronic neurodegenerative disease of the optic nerve and a leading cause of irreversible blindness. Although therapeutic modulation of neuroinflammation is increasingly viewed as a logical strategy to avoid inflam...

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Detalles Bibliográficos
Autores principales: Yang, Xiangjun, Zeng, Qun, Barış, Mine, Tezel, Gülgün
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456390/
https://www.ncbi.nlm.nih.gov/pubmed/32859212
http://dx.doi.org/10.1186/s12974-020-01930-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456390/
https://www.ncbi.nlm.nih.gov/pubmed/32859212
http://dx.doi.org/10.1186/s12974-020-01930-1

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