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Transgenic inhibition of astroglial NF-κB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma
BACKGROUND: Glia-driven neuroinflammation promotes neuron injury in glaucoma that is a chronic neurodegenerative disease of the optic nerve and a leading cause of irreversible blindness. Although therapeutic modulation of neuroinflammation is increasingly viewed as a logical strategy to avoid inflam...
Autores principales: | Yang, Xiangjun, Zeng, Qun, Barış, Mine, Tezel, Gülgün |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456390/ https://www.ncbi.nlm.nih.gov/pubmed/32859212 http://dx.doi.org/10.1186/s12974-020-01930-1 |
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