Cargando…

How accurate is circular dichroism-based model validation?

Circular dichroism (CD) spectroscopy is highly sensitive to the secondary structure (SS) composition of proteins. Several methods exist to either estimate the SS composition of a protein or to validate existing structural models using its CD spectrum. The accuracy and precision of these methods depe...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagy, Gabor, Grubmüller, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456416/
https://www.ncbi.nlm.nih.gov/pubmed/32844286
http://dx.doi.org/10.1007/s00249-020-01457-6