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How accurate is circular dichroism-based model validation?
Circular dichroism (CD) spectroscopy is highly sensitive to the secondary structure (SS) composition of proteins. Several methods exist to either estimate the SS composition of a protein or to validate existing structural models using its CD spectrum. The accuracy and precision of these methods depe...
Autores principales: | Nagy, Gabor, Grubmüller, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456416/ https://www.ncbi.nlm.nih.gov/pubmed/32844286 http://dx.doi.org/10.1007/s00249-020-01457-6 |
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