Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway

Cholesterol is the major component of lipid rafts. Squalene synthase (SQS) is a cholesterol biosynthase that functions in cholesterol biosynthesis, modulates the formation of lipids rafts and promotes lung cancer metastasis. In this study, we investigated the lipid raft-associated pathway of SQS in...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Fang, Chang, Yu-Chan, Jan, Yi-Hua, Yang, Chih-Jen, Huang, Ming-Shyan, Hsiao, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456423/
https://www.ncbi.nlm.nih.gov/pubmed/32862200
http://dx.doi.org/10.1038/s41389-020-00262-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456423/
https://www.ncbi.nlm.nih.gov/pubmed/32862200
http://dx.doi.org/10.1038/s41389-020-00262-2

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