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Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis
BACKGROUND: Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease as well as Lou Gehrig's disease, is a progressive neurological disorder selectively affecting motor neurons with no currently known cure. Around 20% of the familial ALS cases arise from dominant mutations in the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456458/ https://www.ncbi.nlm.nih.gov/pubmed/32862101 http://dx.doi.org/10.1016/j.ebiom.2020.102980 |