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Serum amyloid A inhibits astrocyte migration via activating p38 MAPK
BACKGROUND: The accumulation of astrocytes around senile plaques is one of the pathological characteristics in Alzheimer’s disease (AD). Serum amyloid A (SAA), known as a major acute-phase protein, colocalizes with senile plaques in AD patients. Here, we demonstrate the role of SAA in astrocyte migr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456509/ https://www.ncbi.nlm.nih.gov/pubmed/32861245 http://dx.doi.org/10.1186/s12974-020-01924-z |