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Serum amyloid A inhibits astrocyte migration via activating p38 MAPK

BACKGROUND: The accumulation of astrocytes around senile plaques is one of the pathological characteristics in Alzheimer’s disease (AD). Serum amyloid A (SAA), known as a major acute-phase protein, colocalizes with senile plaques in AD patients. Here, we demonstrate the role of SAA in astrocyte migr...

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Detalles Bibliográficos
Autores principales: Lin, Aihua, Liu, Jin, Gong, Ping, Chen, Yanqing, Zhang, Haibo, Zhang, Yan, Yu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456509/
https://www.ncbi.nlm.nih.gov/pubmed/32861245
http://dx.doi.org/10.1186/s12974-020-01924-z