Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus

OBJECTIVE AND DESIGN: Human stem cell-derived hepatocyte-like cells (HLCs) have shown high potential as authentic model for dissection of the HCV life cycle and virus-induced pathogenesis. However, modest HCV replication, possibly due to robust innate immune responses, limits their broader use. To o...

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Detalles Bibliográficos
Autores principales: Carpentier, Arnaud, Sheldon, Julie, Vondran, Florian W R, Brown, Richard JP, Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456736/
https://www.ncbi.nlm.nih.gov/pubmed/32114504
http://dx.doi.org/10.1136/gutjnl-2019-319354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456736/
https://www.ncbi.nlm.nih.gov/pubmed/32114504
http://dx.doi.org/10.1136/gutjnl-2019-319354

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