TGF-β2 silencing to target biliary-derived liver diseases

OBJECTIVE: TGF-β2 (TGF-β, transforming growth factor beta), the less-investigated sibling of TGF-β1, is deregulated in rodent and human liver diseases. Former data from bile duct ligated and MDR2 knockout (KO) mouse models for human cholestatic liver disease suggested an involvement of TGF-β2 in bil...

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Detalles Bibliográficos
Autores principales: Dropmann, Anne, Dooley, Steven, Dewidar, Bedair, Hammad, Seddik, Dediulia, Tatjana, Werle, Julia, Hartwig, Vanessa, Ghafoory, Shahrouz, Woelfl, Stefan, Korhonen, Hanna, Janicot, Michel, Wosikowski, Katja, Itzel, Timo, Teufel, Andreas, Schuppan, Detlef, Stojanovic, Ana, Cerwenka, Adelheid, Nittka, Stefanie, Piiper, Albrecht, Gaiser, Timo, Beraza, Naiara, Milkiewicz, Malgorzata, Milkiewicz, Piotr, Brain, John G, Jones, David E J, Weiss, Thomas S, Zanger, Ulrich M, Ebert, Matthias, Meindl-Beinker, Nadja M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456737/
https://www.ncbi.nlm.nih.gov/pubmed/31992593
http://dx.doi.org/10.1136/gutjnl-2019-319091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456737/
https://www.ncbi.nlm.nih.gov/pubmed/31992593
http://dx.doi.org/10.1136/gutjnl-2019-319091

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