Detection of Tumor NTRK Gene Fusions to Identify Patients Who May Benefit from Tyrosine Kinase (TRK) Inhibitor Therapy

Chromosomal rearrangements involving the NTRK1, NTRK2, and NTRK3 genes (NTRK genes), which encode the high-affinity nerve growth factor receptor (TRKA), brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) growth factor receptor (TRKB), and neurotrophin-3 (NT-3) growth factor receptor (TRKC)...

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Detalles Bibliográficos
Autores principales: Hsiao, Susan J., Zehir, Ahmet, Sireci, Anthony N., Aisner, Dara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456740/
https://www.ncbi.nlm.nih.gov/pubmed/31075511
http://dx.doi.org/10.1016/j.jmoldx.2019.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456740/
https://www.ncbi.nlm.nih.gov/pubmed/31075511
http://dx.doi.org/10.1016/j.jmoldx.2019.03.008

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