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Specific Targeting of Notch Ligand-Receptor Interactions to Modulate Immune Responses: A Review of Clinical and Preclinical Findings

Understanding and targeting Notch signaling effectively has long been valued in the field of cancer and other immune disorders. Here, we discuss key discoveries at the intersection of Notch signaling, cancer and immunology. While there is a plethora of Notch targeting agents tested in vitro, in vivo...

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Detalles Bibliográficos
Autores principales: Goruganthu, Mounika U. L., Shanker, Anil, Dikov, Mikhail M., Carbone, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456812/
https://www.ncbi.nlm.nih.gov/pubmed/32922403
http://dx.doi.org/10.3389/fimmu.2020.01958