Porcine IFI16 Negatively Regulates cGAS Signaling Through the Restriction of DNA Binding and Stimulation

The innate immunity DNA sensors have drawn much attention due to their significant importance against the infections with DNA viruses and intracellular bacteria. Among the multiple DNA sensors, IFI16, and cGAS are the two major ones, subjected to extensive studies. However, these two DNA sensors in...

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Detalles Bibliográficos
Autores principales: Zheng, Wanglong, Zhou, Rongyun, Li, Shuangjie, He, Shan, Luo, Jia, Zhu, Meiqin, Chen, Nanhua, Chen, Hongjun, Meurens, François, Zhu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456882/
https://www.ncbi.nlm.nih.gov/pubmed/32922386
http://dx.doi.org/10.3389/fimmu.2020.01669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456882/
https://www.ncbi.nlm.nih.gov/pubmed/32922386
http://dx.doi.org/10.3389/fimmu.2020.01669

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