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Modulation of the Aβ-Peptide-Aggregation Pathway by Active Compounds From Platycladus orientalis Seed Extract in Alzheimer’s Disease Models

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by neuronal loss, cognitive impairment, and aphasia. Aggregation of β-amyloid (Aβ) peptide in the brain is considered a key mechanism in the development of AD. In the past 20 years, many compounds have been developed to inhibit Aβ...

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Detalles Bibliográficos
Autores principales: Yan, Li, He, Xiang, Jin, Yufan, Wang, Jiawei, Liang, Fengying, Pei, Rongrong, Li, Peibo, Wang, Yonggang, Su, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456918/
https://www.ncbi.nlm.nih.gov/pubmed/32922281
http://dx.doi.org/10.3389/fnagi.2020.00207