mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer

Mechanistic target of rapamycin (mTOR) signaling pathway mediates the function of oncogenic receptor tyrosine kinases (RTKs). We aimed to elucidate new role of mTOR in EGFR-mutant (EGFR-mut) non-small cell lung cancer (NSCLC) and glioblastoma (GBM) with a focus on tumor microenvironments. Here, we r...

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Detalles Bibliográficos
Autores principales: Cong, Ying, Li, Qingrou, Zhang, Xuesai, Chen, Yaqing, Yu, Ker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456926/
https://www.ncbi.nlm.nih.gov/pubmed/32923403
http://dx.doi.org/10.3389/fonc.2020.01615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456926/
https://www.ncbi.nlm.nih.gov/pubmed/32923403
http://dx.doi.org/10.3389/fonc.2020.01615

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