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mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer

Mechanistic target of rapamycin (mTOR) signaling pathway mediates the function of oncogenic receptor tyrosine kinases (RTKs). We aimed to elucidate new role of mTOR in EGFR-mutant (EGFR-mut) non-small cell lung cancer (NSCLC) and glioblastoma (GBM) with a focus on tumor microenvironments. Here, we r...

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Detalles Bibliográficos
Autores principales:	Cong, Ying, Li, Qingrou, Zhang, Xuesai, Chen, Yaqing, Yu, Ker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456926/ https://www.ncbi.nlm.nih.gov/pubmed/32923403 http://dx.doi.org/10.3389/fonc.2020.01615

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